​Department of Biotechnology and Biosciences

Metabolite libraries built from NMR spectra for the metabolomics analysis of cinnamon extracts, using the Simple Mixture Analysis (SMA) tool implemented in MestreNova 14.1 software.

Structure of bombesin peptide calculated in presence of 150 mM SDS micelles at pH 7.0, 25°C. Structure was determinded by NMR spectroscopy and SA-MD. Data clearly show that, under these experimental conditions, bombesin adopts a α-helix structure.

Metabolite libraries built from NMR spectra for natural, lavado and commercial cocoa and for two extraction procedures (hydroalcoholic and Soxhlet), using the Simple Mixture Analysis (SMA) tool implemented in MestreNova 12.4 software.

The .diam files are the creter diameters to be used with the software craterstats2 The olimpo_nocart.exe is the executable to calculate the water splash; input data are requested when running the code; the txt files should not be modified The runup_water_acheron6_pss is a small fortran code to calculate the run-up and velocity of the water wave with the analytical formula provided in the text

Metabolite library built from NMR spectra for metabolomic analysis of leaves' hydroalcholic extract (80% MeOH) from wild mountain Mentha longifolia, using the Simple Mixture Analysis (SMA) tool implemented in MestreNova 14.1 software.

Metabolite library built from NMR spectra for metabolomic analysis of leaves' aquous extract from Lolium multiflorum, using the Simple Mixture Analysis (SMA) tool implemented in MestreNova 14.1 software.

Metabolite libraries built from NMR spectra for two types of coffee (green or roasted) and for three extraction procedures (hydroalcoholic, espresso, moka), using the Simple Mixture Analysis (SMA) tool implemented in MestreNova 12.0 software.

Revision of Hydatigera taeniaeformis species complex with a description of a new species (Lavikainen et al., IJP 2016): 1. Morphological data. A drawing (atypical segment). Morphological matrix. 2. DNA data. Nucleotide sequence alignments (18S rDNA; pold & pepck; mitochondrial protein-coding genes; cox1 complete haplotype data set).

dataset contains Clinical and molecular characteristics of patients affected by neurofibromatosis and studied by next generation sequencing (NGS) panel including NF1, NF2, SPRED1, SMARCB1, and LZTR1 genes on Ion Torren

The hippocampus is a brain area central for cognition. Mutations in the human SOX2 transcription factor cause neurodevelopmental defects, leading to intellectual disability and seizures, together with hippocampal dysplasia. We generated an allelic series of Sox2 conditional mutations in mouse, deleting Sox2 at different developmental stages. Late Sox2 deletion (from E11.5, via Nestin-Cre) affects only postnatal hippocampal development; earlier deletion (from E10.5, Emx1-Cre) significantly reduces the dentate gyrus (DG), and the earliest deletion (from E9.5, FoxG1-Cre) causes drastic abnormalities, with almost complete absence of the DG. We identify a set of functionally interconnected genes (Gli3, Wnt3a, Cxcr4, p73 and Tbr2), known to play essential roles in hippocampal embryogenesis, which are downregulated in early Sox2 mutants, and (Gli3 and Cxcr4) directly controlled by SOX2; their downregulation provides plausible molecular mechanisms contributing to the defect. Electrophysiological studies of the Emx1-Cre mouse model reveal altered excitatory transmission in CA1 and CA3 regions.