University of Milano-Bicocca Showcase

# Raw Raman Spectra of Fluid and Melt Inclusions in Mantle Peridotites from Sal Island (Cape Verde) This dataset contains approximately 553 unprocessed Raman spectra acquired from Type I and Type II fluid-rich melt inclusions hosted in mantle peridotite xenoliths from Sal Island, Cape Verde. The data constitute the primary Raman spectroscopic records supporting the published study by Maffeis et al. (2026), Carbon enrichment processes in the oceanic upper mantle preserved in peridotites from Sal Island (Cape Verde), Geoscience Frontiers, 17, 102179 (https://doi.org/10.1016/j.gsf.2025.102179), and provide source data for further publications currently in preparation. The investigated inclusions record interactions between mantle peridotites and infiltrating volatile-rich silicate–carbonate metasomatic melts. Type I inclusions, predominantly hosted in olivine, contain silicate glass, variable carbonate phases, and CO2-rich fluids with subordinate CO and N2. Type II inclusions, hosted in relic orthopyroxene within metasomatic reaction domains, contain silicate glass and secondary mineral phases associated with CO2-CO fluids, locally characterised by elevated CO concentrations and carbonaceous material. The database includes Raman spectra of fluid species, silicate and carbonate phases, and other solid components identified within or associated with the inclusions. Spectral measurements encompass different Raman-shift intervals according to the analytical targets and the spectral features observed during acquisition. Each spectrum is provided as an individual plain-text file containing two numerical columns: Raman shift (cm-1) and measured Raman intensity (counts). The data are supplied in their original, unprocessed form, without baseline subtraction, spectral smoothing, peak fitting, or intensity normalisation. File names retain the original analytical identifiers, including combinations of sample identification, host mineral, inclusion number, analytical spot, and/or analysed component. Although naming conventions are not entirely uniform, the identifiers preserve sufficient information to reconstruct the relationships between samples, inclusions, analysed phases, and individual Raman measurements.

Dataset C3 membranous

Dataset for the development of the algorithm in the study "Machine Learning for Monoclonal Gammopathies of Renal Significance Risk Stratification Using Clinical and Pathology Data"

This repository contains MALDI mass spectrometry imaging (MALDI-MSI) data acquired from a clear cell renal cell carcinoma (ccRCC) tissue section. The dataset comprises spatially resolved mass spectra of lipids, N-glycans, and tryptic peptides obtained from the same tissue section using a multi-omics imaging workflow. These complementary molecular layers enable the characterization of distinct histological regions, including healthy renal cortex, renal capsule, and tumor tissue. In particular: FinalMatrix_Coor.RDS contains pixel coordinates. FinalMatrix_Coor_reverseX.RDS contains the same coordinates flipped along the x-axis to match the orientation of the H&E-stained tissue image. FinalMatrix_Lipids.RDS, FinalMatrix_Glycans.RDS, and FinalMatrix_Peptides.RDS contain transformed molecular abundances for each pixel. Each row corresponds to a pixel and each column to an m/z value. list_ind_resolution_4123.RDS and list_ind_resolution_4123_cpp.RDS contain the indices of neighboring pixels for each pixel. The former uses 1-based indexing, whereas the latter uses 0-based indexing. These data were analyzed in the study “Multiomics Tissue Segmentation via Spatially-Informed Nested Biclustering Methods” by Francesco Denti, Cecilia Balocchi, Vanna Denti, and Giulia Capitoli, published in Biometrics. Preprint: https://fradenti.github.io/pdf/Poseidon.pdf Analysis code: https://github.com/Fradenti/poseidon-maldi

This dataset has been used in the manuscript titled “Snow Surface Parameters from PRISMA Data in the Alps and Their Implications for Radiative Forcing” and provides snow property parameters retrieved from PRISMA hyperspectral imagery acquired over Plateau Rosa (Aosta Valley, European Alps) following a Saharan dust deposition event in July 2024. The parameters include mineral dust concentration, snow grain size, broadband albedo, and instantaneous radiative forcing. These were estimated using a supervised learning approach based on the K-Nearest Neighbors (KNN) algorithm, which was applied to match observed spectra with a reference library generated using the BioSNICAR radiative transfer model. The dataset also includes Asymptotic Radiative Transfer (S-ART) model (S-ART) outputs and in situ measurements collected during a dedicated field campaign. These data support the investigation of the effects of light-absorbing impurities on snow radiative properties, contributing to the improvement of climate and hydrological modeling in high-altitude environments.

The present refers to a study that investigated whether facial identity and emotional expressions impose different cognitive demands during working memory updating and maintenance, how emotional information decays, and whether different emotions differentially affect performance. Fifty-six healthy adults completed an n-back task in which they monitored facial identity, emotional expression, or both simultaneously under three levels of cognitive load. Accuracy and response times were analyzed as indices of working memory performance. Results revealed that performance was significantly lower when emotion was the only relevant information, indicating that emotional information requires greater cognitive resources to be maintained and updated. Interestingly, processing both identity and emotion simultaneously resulted in better performance than processing emotional information alone, suggesting a potential binding mechanism between facial identity and emotional expression. Furthermore, longer response times were associated with lower accuracy independently of cognitive load, a pattern consistent with time-based accounts of working memory decay. Finally, no significant differences in performance emerged among different facial expressions. These findings suggest that emotional information imposes greater working memory demands than identity alone or emotion-identity combined, support a main role of temporal factors in the decay of social-emotional information, and indicate that the maintenance of emotional expressions in working memory may be relatively insensitive to differences in emotional valence.

The dataset contains field observations of pollinator visitation to 43 ornamental plant species surveyed across seven Italian cities during May. Data include information on plant identity, green area type and habitat characteristics, together with pollinator abundance, richness, and taxonomic/group-level visitation records. The dataset also includes floral trait measurements used to investigate plant–pollinator relationships, including morphological and resource-related traits. These data allow the assessment of the relative attractiveness of ornamental plants for urban pollinators and the role of plant traits and urban habitat context in shaping pollinator communities. Authors contributing to this dataset are: Paolo Biella 1*, Giulia Brambilla 1, Valentina Verduci 2,12, Matteo Annessi 3, Andrea Beltramini 4, Lorenzo Bianco 5, Daniele Calabrese 6, Francesca Romana Dani 4,2, Marta Depetris 7, Andrea Di Giulio 3,2, Andrea Ferrari 8, Jessica Frigerio1, Gianni Henson 6, Martino Maggioni 4,2,12, Francesca Martelli 3, Oana Catalina Moldoveanu 4, Jorge Sanchez Navarro 10,2, Massimo Nepi 2,6, Emily Rose Palm1, Irene Piccini 9,5, Carlo Polidori 8,2, Michelina Pusceddu 10,2, Fausto Ramazzotti 1, Enrico Ruzzier 2,3, Alberto Satta 10,2, Giovanni Scopece 11,2, Carla Sorvillo 2,11, Elena Tafi 6,2, Andrea Galimberti 1,2, Davide Maggioni 1,2, Massimo Labra 1,2 1 Department of Biotechnology and Biosciences, University of Milano-Bicocca, Italy 2 National Biodiversity Future Center, University of Palermo, Italy 3 Department of Science, Roma Tre University, Rome, Italy 4 Department of Biology, University of Florence, Italy 5 Department of Life Sciences and System Biology, University of Turin 6 Department of Life Sciences, University of Siena, Siena, Italy 7 independent researcher, Turin, Italy 8 Department of Environmental science and policy, University of Milano 9 Department of Zoology, Poznań University of Life Sciences, Poznań, Poland 10 Department of Agricultural Sciences, University of Sassari, Sassari, Italy 11 Department of Biology, University of Naples Federico II, Italy 12 Earth and Marine Sciences Department, University of Palermo, Palermo, Italy

Iterative Bleaching Extends Multiplexity (IBEX) immunofluorescence was performed on skin samples collected from CD11c-DOG mice either treated with diphtheria toxin (Skin_CD11cDOG_with_Diphtheria_Toxin) or phosphate-buffered saline (PBS) treated controls (Skin_CD11cDOG_no_Diphtheria_Toxin). For dendritic cell depletion, CD11c-DOG mice received three systemic intravenous injections of diphtheria toxin (16 ng/g body weight) on days −3, −2, and −1. Control mice PBS following the same schedule. In addition, a local subcutaneous injection of diphtheria toxin (16 ng) was administered on day −1 at the site designated for tissue collection. Mice were euthanized on day 0 in accordance with national and international regulations for animal care and use. A square section of flank skin was excised from each mouse at the site of the last intradermal injection. Subcutaneous adipose tissue was mechanically removed using forceps. Skin samples were subsequently processed according to the 2D Manual IBEX protocol for multiplex immunofluorescence imaging.

Live-cell holotomographic imaging of OHP-induced pathological changes in DRG neurons. These videos show primary adult mouse DRG neuronal cultures exposed to OHP at 7.5 or 25 µM. Refractive index-based imaging captures neurite fragmentation and degeneration, morphological features consistent with necroptosis, and autophagic vacuoles. Images were acquired using a 5 × 5 grid scan, with each grid measuring 90 × 90 µm, every 15 min for 28 h at 7 fps, from 24 to 52 h after OHP incubation.